After a guitar course, Diego Salamanca trained on the lute with Armando Fuentes at the Javeriana University of Bogota, before continuing his studies at the Conservatoire National Supérieur de Musique de Lyon in the class of Eugène Ferré, where he successively obtained his diplomas in baroque lute in 2006 and renaissance lute in 2008. Attracted by the baroque repertoire for the lute and plucked string instruments, he is particularly devoted to French and Germanic music of the 17th and 18th centuries.

Also focused on the practice of accompaniment on instruments of the lute family and the creation of basso continuo, particularly on the theorbo, he regularly participates in productions of stage or chamber music, as well as in recordings. Among others, he has performed under the direction of Phillip Picket, Christophe Coin, Gabriel Garrido, William Christie, Kenneth Weiss, Gérard Lesne, Skip Sempé, Alessandro de Marchi, François Lazarevitch.

His solo CD dedicated to S. L. Weiss has received a Diapason "discovery".